A group of people

Glossary of terms

F

Finance Income and Expense

Includes interest earned and payable, and similar items.

First Good Laboratory Practice (FGLP)

The point at which a compound undergoes the fi rst pre-clinical study that is required for regulatory approval, which marks entry into the development pipeline.

First-Line Therapy

Treatment given to a newly diagnosed patient, who has therefore not yet been treated.

First Time in Man

The first time that an experimental compound is administered to a human. It implies that the compound has passed ethical review bodies and passed formal regulatory toxicology studies.

Food and Drug Administration (FDA)

Part of the US Department of Health and Human Services Agency responsible for development, approval, manufacture, sale and use of all drugs, biologics, vaccines and medical devices in the US.

Free Cash Flow

Represents net cash flows before financing activities, and is calculated as: net cash inflow before financing activities, adjusted for acquisitions of businesses, movements in short term investments and fixed deposits and disposal of intangible assets.