A
- Abbreviated New Drug Application (ANDA)
- A marketing approval application for a generic drug submitted to the US Food and Drug Administration.
- ACE (Inhibitor)
- A class of drugs that is used to treat hypertension and other cardiovascular diseases, which work by blocking the production of a hormone called angiotensin II.
- acute coronary syndrome (ACS)
- An umbrella term used to cover any group of clinical symptoms compatible with acute myocardial ischaemia.
- adenosine diphosphate (ADP)
- A molecule that plays an important role in energy transfer in cells.
- Adjuvant
- An agent that modifi es the effect of other agents (for example drugs and vaccines) while having few if any direct effects when given by itself; it operates like a catalyst in chemical reactions.
- Adjuvant therapy
- Treatment given as an adjunct to another medical intervention, for example surgery.
- ADR
- American Depositary Receipt evidencing title to an ADS.
- ADS
- American Depositary Share representing one underlying Ordinary Share.
- Adverse reaction
- An unwanted, negative consequence associated with the use of a medicine.
- Agonist
- A substance capable of binding to a molecular target to initiate or enhance a physiological reaction.
- Allergic rhinitis
- An allergic reaction to airborne substances such as pollen or dust.
- Alzheimer’s disease
- A group of disorders causing deterioration of the brain, which affects one’s memory and reasoning capabilities.
- Anaesthesia
- The total or partial loss of sensation, especially in relation to pain.
- Analgesia
- The inability to feel pain whilst conscious.
- Angina
- Chest pain/discomfort caused by lack of oxygen to the heart muscles through reduced blood fl ow in the coronary arteries.
- Angiogenesis
- A physiological process in which new blood vessels grow from pre-existing vessels.
- angiotensin converting enzyme (ACE)
- Converts a hormone called angiotensin to its activated form called angiotensin II, enabling it to function. Angiotensin II acts by narrowing the diameter of the blood vessels and thereby raises blood pressure.
- Angiotensin II
- A hormone that causes blood vessels to narrow and thereby raises blood pressure.
- Ankylosing spondylitis
- A degenerative inflammatory disease affecting the spine and causing chronic pain.
- Antagonist
- A substance capable of binding to a molecular target to neutralise or counteract a physiological reaction.
- Anti-androgen
- A drug that blocks the cellular uptake of testosterone by the prostate gland and used in the treatment of prostate cancer.
- Anti-psychotic drug
- A drug for the treatment of depression or mania.
- Aromatase inhibitor
- A drug that inhibits the enzyme, aromatase, which is involved in the production of
the female sex hormone, oestrogen and therefore is used in the treatment of breast cancer. - AstraZeneca or AstraZeneca Group
- AstraZeneca PLC and its subsidiaries.
- Atherosclerosis
- The progressive narrowing or hardening of the arteries linked to the build-up of
lipids (fats) in the arterial walls and the formation of atheromatous plaque. - Atherosclerotic plaque
- A build up of cholesterol and fatty material in the walls of blood vessels as a consequence of atherosclerosis.
- Atrial fibrillation (AF)
- Abnormal irregular heart rhythm.
- Atypical anti-psychotic drugs
- Second generation drugs to treat psychosis with reduced likelihood to cause movement disorders.
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At 20-Nov-2009 23:29 GMT
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