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26 June 2008
AstraZeneca Announces Senior Management Changes at Biologics Business Unit, MedImmune

Dave Mott to leave AstraZeneca, Tony Zook takes over as interim head of MedImmune

AstraZeneca today announced that Dave Mott, President and Chief Executive Officer (CEO) of its biologics business unit, MedImmune, has decided to leave the company at the end of July. Tony Zook, CEO of AstraZeneca’s North American business and Executive Vice President of Global Marketing, has been appointed as head of MedImmune on an interim basis until a permanent successor is identified.

David Brennan, CEO of AstraZeneca, said: “Under Dave Mott’s leadership, the team at MedImmune has built a unique capability to discover, develop and deliver innovative biologic treatments – an important element of AstraZeneca’s future strategy. We will continue to build on that strong platform, maximising the potential of products in the MedImmune portfolio while delivering innovative new biological medicines and vaccines that treat and prevent disease.”

Since the acquisition in June 2007, AstraZeneca’s previous investment in Cambridge Antibody Technology and the company’s other internal biologics resources have been integrated into MedImmune to create a world-class biologics business. During the same period, MedImmune has submitted a Biologics License Application (BLA) to the US FDA for motavizumab, an investigational monoclonal antibody (MAb) derived from recombinant DNA technology.


-ENDS-

CONTACTS:
Media Enquiries:
Steve Brown +44 207 304 5033 (24 hours)
Chris Sampson +44 20 7304 5130 (24 hours)
Neil McCrae +44 207 304 5045 (24 hours)

Investor Enquiries UK:
Jonathan Hunt +44 207 304 5087 mob: +44 7775 704032
Mina Blair +44 20 7304 5084 mob: +44 7718 581021
Karl Hard +44 207 304 5322 mob: +44 7789 654364

Investor Enquiries US:
Ed Seage +1 302 886 4065 mob: +1 302 373 1361
Jorgen Winroth +1 212 579 0506 mob: +1 917 612 4043
Peter Vozzo (MedImmune) +1 301 398 4358 mob: +1 301 252 7518

Notes To Editors
About AstraZeneca
AstraZeneca is a major international healthcare business engaged in the research, development, manufacturing and marketing of meaningful prescription medicines and supplier for healthcare services. AstraZeneca is one of the world's leading pharmaceutical companies with healthcare sales of $29.55 billion and is a leader in gastrointestinal, cardiovascular, neuroscience, respiratory, oncology and infectious disease medicines. For more information about AstraZeneca, please visit: www.astrazeneca.com

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