As Head of IT for Drug Development and Digital Health, I lead a global technology team in implementing innovative solutions across clinical development, regulatory affairs, patient safety and R&D portfolio management.

I am a passionate technologist with broad experience across multiple industries, harnessing the power of digital to tackle previously untapped opportunities. In my opinion, there is nowhere more exciting than working at the intersection of technology and healthcare, with patients at the heart of everything we do. 

Since joining AstraZeneca in 2015, I have been at the forefront of digital transformation initiatives in Commercial and R&D. My focus is on applications of digital, data, and AI to accelerate the development of our medicines, and reimagine the patient experience in the clinic and real-world settings. 

Emphasizing agile methodologies and fit-for-future technologies enables us to lead in a digitally disrupted space. Our multi-year IT transformation has already established the foundation for our start-up, growth-oriented mindset where we are actively investing in key capabilities such as software and data engineering, data science and AI, technology strategists and architects. 

As a leader, I foster an environment of diversity and inclusion and promote an intellectually-rigorous culture. Our team is designed to thrive in a space where we continuously adapt and embrace constant change.

Together we are pushing the boundaries of science and revolutionizing healthcare.

Working closely with R&D, Operations and Commercial colleagues, my IT team harnesses the power of digital, data and AI to improve patient health outcomes across the globe.

Sean Connolly Head of IT for Drug Development and Digital Health

CIO Magazine ‘CIO 100’ Winner

Received in 2016 for ‘PIVOT’ R&D Portfolio Management Solution

AstraZeneca CIO Award – Digital Innovation

Received in 2017 for Veeva Global Medical CRM

AstraZeneca CEO Award

Received in 2020 for Bridge to the New Normal – Accelerated Adoption of Digital Across Our Business


Head of Information Technology for Drug Development and Digital Health at AstraZeneca


In partnership with R&D, led the IT transformation and technical implementation of digital solutions across clinical drug development, accelerating studies by median of nine months, reducing cost of phase III trials by 20%. Successfully implemented the largest IT systems change in history of AstraZeneca R&D, the first pharma to align Japan clinical trial management with one global solution.


Delivered Global Medical Affairs CRM and Real World Evidence data and analytics capabilities as IT Capability Lead for AstraZeneca Global Medical Affairs.


Implemented a cross-discipline high performance research computing infrastructure ‘Colonial One’ while serving as Executive Director of Information Technology for Research Computing at George Washington University.