Eosinophil-Driven Diseases (EDDs)

Our ambition to address unmet needs for people with EDDs

Our commitment to eosinophil-driven diseases

Building on a 50-year heritage in respiratory care and following the science of common pathways and underlying disease drivers from respiratory disease into immunology-driven disease areas, we’re continuing to better understand the important role of eosinophils as key effector cells in a range of potentially devasting inflammatory diseases, also known as eosinophil-driven diseases (EDDs).

EDDs are inflammatory illnesses in which elevated eosinophils are a direct cause or are thought to play a critical role.1 Some EDDs have limited or no approved treatment options, creating a significant unmet need for innovative medicines. We know now that a process called eosinophilic immune dysfunction may be responsible for the eosinophil recruitment and activation that is driving these diseases. Backed by a growing body of evidence, we’re committed to advancing the understanding of the role of eosinophils in inflammatory diseases across Respiratory & Immunology, with the aim to improve diagnosis, patient referrals and timely, appropriate treatment.


Patient Portraits

Types of eosinophil-driven diseases

We are currently investigating potential medicines to treat inflammatory, EDDs where unmet medical need remains significant and, in some cases, where we see an increasing prevalence.

Join us

At AstraZeneca, we’re driven by innovation and our commitment to make a real-life difference in patients’ lives. Join us and help deliver life-changing medicines. Be among our employees who continue to make us an innovation-driven company that stands firmly among the world’s leaders in biopharmaceuticals. 


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