Lauren Drowley is an Associate Principal Scientist in the Cardiac Regeneration team at AstraZeneca in Gothenburg, Sweden.

Lauren received her PhD on stem cell transplantation for myocardial infarct repair from University of Pittsburgh. This was followed by a postdoctoral position at AstraZeneca in the UK, where she developed high content imaging assays with stem/progenitor cell populations for diabetes/obesity indications and examined the role of miRNA in cell differentiation.

In her current role as a stem cell specialist, she is characterising primary adult and iPS-derived stem cell populations, developing and implementing phenotypic proliferation and differentiation assays for cardiac repair, and assessing potential drug targets. In addition, she serves as biology lead on several drug projects and manages collaborations with academic partners.

  Searching for a cure for heart failure


A cure for heart failure


Developing stem cell-based phenotypic assays


Characterizing cardiac progenitor cell populations


SLAS Young Scientist 2011

  Featured Publications

Human Myogenic Endothelial Cells Exhibit Chondrogenic and Osteogenic Potentials

Human Myogenic Endothelial Cells Exhibit Chondrogenic and Osteogenic Potentials at the Clonal Level. Bo Zheng, Guangheng Li, William C.W. Chen, Bridget M. Deasy,Jonathan B. Pollett, Bin Sun, Lauren Drowley, Burhan Gharaibeh,Arvydas Usas, Bruno Pe ́ault, Johnny Huard. Journal of Orthopaedic Research 2013; 31(7): 1089-95. DOI: 10.1002/jor.22335

Loading stem cells to improve transplantation outcome

Mechanical loading of stem cells for improvement of transplantation outcome in a model of acute myocardial infarction: the role of loading history. Theresa R Cassino, Lauren Drowley, Masaho Okada, Sarah A Beckman, Bradley Keller, Kimimasa Tobita, Philip R Leduc, Johnny Huard. Tissue Engineering Part A. 2012; 18(11-12):1101-8. DOI: 10.1089/ten.TEA.2011.0285

Skeletal muscle cells improve ischemic heart function

Human skeletal muscle cells with a slow adhesion rate after isolation and an enhanced stress resistance improve function of ischemic hearts. Masaho Okada, Thomas R Payne, Lauren Drowley, Ron J Jankowski, Nobuo Momoi, Sarah Beckman, William C W Chen, Bradley B Keller, Kimimasa Tobita, Johnny Huard. Molecular Therapy 2011; 20(1):138-45. DOI: 10.1038/mt.2011.229

Science Star

AstraZeneca 2014

Young Scientist Poster Award

Society for Laboratory Automation and Screening, 2011

NIH predoctoral training grant

Cellular Approaches to Tissue Engineering and Regeneration

I am really excited about the work in cardiac regeneration – the focus on using cells derived from patients and the use of phenotypic screening will allow us to identify both novel and biologically relevant compounds that could really help patients in the future.

Lauren Drowley