African Cluster

AstraZeneca is a global innovation driven biopharmaceutical company pushing the boundaries of science to deliver life-changing medicines.

Science can change our vision of the world and how we deal with the diseases that affect us. The future of treatment for many of today’s diseases lies in uncovering disease mechanisms that are newly emerging or are still to be discovered. Science challenges us to push the limits of what is possible. This is why we put science at the centre of everything we do.

At AstraZeneca every one of our employees makes a difference to patient lives every day. We are inspired by the things that seem impossible and stimulate continued creativity throughout our organisation, maintaining a culture in which our people feel valued for their ideas and contributions. Ideas that can make a difference in all aspects of our business and to healthcare in Africa.

Our regional and country offices serve as a hub of communication between our office-based staff and more than half the company's employees that are directly involved in the promotion of our medicines to Healthcare Professionals throughout our markets in our African Cluster.

AstraZeneca has been working to deliver the best value to patients in Africa for over 28 years. Our vision is to transform the lives of patients, ensuring all Africans have access to our innovative medicines.

Contact Details

South Africa

Building 2
Northdowns Office Park
17 Georgian Crescent West
Johannesburg – South Africa

Tel:+27 (0) 11 797 6000
Fax: +27 (0) 86 640 1463


Avenue 5
Rose Avenue

P.O Box 10107, Nairobi, Kenya

Tel:+254 20 2714812

Our Senior management team

Barbara Nel                                    Country President: African Cluster

Alexander Lygin                             CFO: African Cluster

Dr Khomotso Mashilane                Medical Director: African Cluster

Ursula Du Preez                             Primary Care Strategy Director: African Cluster

Contact Barbara Nel                      Business Unit Director Oncology: African Cluster

Contact Barbara Nel                      Human Resources Director: African Cluster

Arpit Bansal                                   Country Director: Sub Saharan Africa

Dr Sylvia Vito                                 Government Affairs and Market Access Director: Sub Sahara and French Speaking Africa

Adélaïde Ehouman                        Country Director: French Speaking Africa

Phumlani Mancapha                      Primary Care Sales Director: South Africa

Ruth Field                                      Government Affairs and Market Access Director: South Africa

Jonathan Calder                            Head of IT & Digital: African Cluster

Reshma Singh                               Compliance Senior Manager:  African Cluster

Nicolene Padayachee                    Senior Legal Counsel: African Cluster


Unlocking the power of what science can do.

We market medicines that are designed to improve the health and quality of life of patients, focusing on 3 main therapy areas: Respiratory; Cardiovascular, Renal and Metabolism (CVRM) with newer treatments in Type 2 Diabetes Mellitus being our core strength; and Oncology with targeted and immune-oncology therapies being the future portfolio in cancer management.


At AstraZeneca, Cardio-Vascular, Renal and metabolism (CVRM) is one of our main therapy areas because science continues to uncover commonalities between cardiovascular, renal and metabolic diseases. With this knowledge, we are daring to do things differently by shifting focus from treating patients with a single disease, to addressing overlapping disease areas and risk factors. This is why we have created a distinct approach to care for Cardiovascular, Renal and Metabolic diseases – CaReMe. This new approach gives us the chance to save vital time and valuable healthcare resources, and most importantly improve patient lives.

Diabetes is a disease of epidemic scale and an important strategic focus for AstraZeneca. With reportedly over 19.4 million adults living with diabetes in Africa in 2019 (IDF Atlas 9th edition), we are focused on redefining the Type 2 diabetes treatment approach and harnessing complementary mechanisms of action, as well as cardiovascular outcomes benefits.

As facilitators of the CaReMe approach, we make it our responsibility to help Healthcare Professionals connect the dots, evolve their clinical practice and provide complete, potentially life-saving care for CVRM patients. Our priority is to empower Healthcare Professionals to diagnose and treat earlier in the course of the disease. It is through partnering with all healthcare stakeholders that we can protect patients against heart and renal failure, improve health and save the lives of patients in Africa living with these diseases.

In South Africa AstraZeneca has partnered with BrandMed a leading South African connected healthcare company that integrates medical and lifestyle expertise and science with ground-breaking technologies. As part of this collaboration AstraZeneca has provided sponsorship towards the establishment of fifteen BrandMed Syntro-P Health Centres of Excellence offering patients access to a more proactive, patient-centric, integrated risk-reduction and treatment approach to chronic conditions.


For more than 40 years we have developed drugs to combat cancer, many of which have increased survival rates for patients around the world. We aim to advance the science of oncology with a combination-focused pipeline set to address the unmet clinical needs in a host of cancers. Our vision is to redefine the cancer treatment paradigm in Africa, with our primary focus on prostate cancer, breast cancer and lung cancer.

In Kenya we are collaborating with the Ministry of Health (MoH) in the roll out of the new Oncology treatment protocols to Healthcare Professionals across the country. The development and dissemination of the treatment protocols will help to standardize practice and ensure universal access to quality cancer care at the MoH facilities.

In South Africa AstraZeneca has a proven track record of working collaboratively and successfully with the Government and health partners to bring medicines for chronic conditions to South African patients in a timely manner and securing expanded access to these medicines via our Phakamisa programme, with a strong focus on Breast and Prostate Cancer.


Our goal is to establish a leading position in Asthma and Chronic Obstructive Pulmonary Disease (COPD) in Africa. We aim to bring scientific education to the medical community, value to the patient, help redefine standards of care and raise awareness of the ongoing unmet medical needs in Asthma and COPD in Africa. We host a variety of forums and meetings annually, highly regarded by the scientific community and attended by prominent respiratory specialists in South Africa and Africa.

AstraZeneca will continue to optimise clinical practice in Africa through a range of medications including differentiated inhaled therapies, novel combinations and devices for asthma and COPD to improve choice and outcomes for patients. Our inhaled treatments are the foundation of our respiratory portfolio in Africa and core to our business.

The respiratory clinical community laid down a challenge to improve asthma care globally in the 2018 Lancet Commission. AstraZeneca shares the belief that there should be zero tolerance for preventable asthma attacks. People living with asthma should have the ability to lead normal lives and deserve the best care. While we recognise that these are long-term goals, we are unwavering in our commitment to improve care for asthma patients across Africa.


We engage extensively with our Healthcare Professionals (HCPs) from participation in clinical trials and as part of our sales and marketing work, ensuring that clinicians have the best access to information about our products in order to make appropriate treatment  decisions, delivering better patient care.

As part of our collaboration and engagement with HCPs we support the development and delivery of medical education services.



  • We have a strong scientific team of qualified Medical Doctors and Specialists providing key scientific support, across our key Therapeutic Areas, to HCPs and our AstraZeneca teams.
  • We collaborate with medical societies to increase awareness of global management guidelines. We continually explore additional areas for collaboration with medical and pharma societies, with the aim of supporting the education of Healthcare Professionals (HCPs).  
  • We have worked extensively to bring some of the best educational resources and key experts to Africa to expand scientific education programmes and knowledge sharing amongst HCPs.
  • The ePD platform in South Africa and Greatminds platform in Sub Sahara, provides doctors access to current, relevant content with international and local speakers. An interactive learning experience utilising technology that offers a solution that best suits doctors’ needs and time.
  • Our AZEngage platform is our online Continuous Professional Development and Training platform for HCPs. The site provides an easy-access platform to view current and accredited CPD videos from the location of choice, expanding our scientific information offering and providing the latest information on medical journal publications.
  • AstraZeneca Africa utilises live Video conferencing platforms to host international speakers, bringing international knowledge to the region and combining this with local expertise.
  • Our HCP portal offers rich content on Cardiovascular Renal and Metabolic (CVRM) diseases, for South African Health Care Professionals.
  • HCP portal offers our Health Care Professionals product related information.


Our Continent’s future social and economic development will depend on an equitable and inclusive healthcare system that is able to respond to the healthcare needs of all Africans.  At AstraZeneca we are committed to working with governments, policy makers and regulatory bodies across our markets to ensure that patients in Africa have access to innovative medicines when they need them.

We want our treatments to improve the lives of as many people as possible. This goal calls for us to actively participate in discussions with governments and healthcare stakeholders on healthcare reform to deliver a sustainable solution that ensures patients encounter fewer barriers to treatment.


At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. In Africa we consider our responsibility to our patients and our community as an integral part of what we do. When we see an opportunity for change we seize it and make it happen, because an opportunity no matter how small can be the start of something big.

Our commitment to improve health outcomes for African patients extends far beyond our medicines. We offer programmes that advance patient health and access along the care continuum and provide reliable support networks.

Programmes active in our African Cluster

Healthy Heart Africa

Developed by AstraZeneca and implemented across Africa in collaboration with African Governments and Non-Governmental Organizations (NGOs), Healthy Heart Africa (HHA) is designed to contribute to the prevention and control of hypertension and decreasing the burden of cardiovascular disease (CVD) across Africa.  Launched in Kenya in 2014, Ethiopia in 2016, Tanzania in 2018, Ghana in 2019, Uganda in 2020 and Côte d'Ivoire, Senegal and Rwanda in 2021, the programme supports sustainable models by working with local health systems.  Each model works independently with partners in the country of implementation to address different health challenges and health environments, with the aim of providing a sustainable means of fighting hypertension in Africa.

In support of the United Nations targets to reduce the risk of premature death from NCDs[1]  along with the Pan-African Society of Cardiology (PASCAR) ‘Roadmap’ to reduce heart disease and stroke [2],  HHA aspires to reach 10 million people with elevated blood pressure by 2025, working together with local and global partners to:

  • Increase awareness and educate around lifestyle choice and CVD risk factors
  • Train providers and drive care to lower levels of the healthcare system
  • Facilitate access to low cost, high quality branded anti-hypertensives

Healthy heart Africa has also embarked on an innovative public-private partnership with the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) to tackle the burden of HIV and hypertension in Africa.  At the foundation of the partnership is a shared commitment to reaching those outside of the traditional entry points to care, with a particular emphasis on men. More information on Healthy Heart Africa in Kenya, Ethiopia Tanzania, Ghana, Uganda, Côte d'Ivoire, Senegal and Rwanda can be found here.

[1]R. L. Sacco et al. The Heart of 25 by 25: Achieving the Goal of Reducing Global and Regional Premature Deaths From Cardiovascular Diseases and Stroke. Circulation. 2016, 11:e674-e690. Available at: Last accessed November 2019.

2 A. Dzudie et al. PASCAR Roadmap on Hypertension. Roadmap to achieve 25% hypertension control in Africa by 2025. Cardiovascular Journal of Africa. 2017. Available at: Last accessed November 2019.

Young Health Programme

Our award-winning AstraZeneca Young Health Programme has a unique focus on young people and primary prevention of the most common non-communicable diseases (NCDs). Working in partnership with global and local organisations, the Young Health Programme works to positively impact the health of adolescents through research, evidence generation, advocacy for change and on-the-ground programmes. The Young Health Programme was launched in Kenya in partnership with Plan International in 2016 and aims to contribute to improved health and gender equality of Nairobi’s Kibera and Mathare informal settlements.

In South Africa and Angola the Young Health Programme partnership with UNICEF aims to catalyse a global advocacy movement led by young people for the promotion of healthier lifestyles. The focus is on raising awareness of key issues, empowering young people to advocate, and taking policy action to create meaningful and lasting change.

More information about the Young Health Programme can be found here

Step Up! Global Grants Programme

Through the Step Up! Global Grants Programme AstraZeneca extends the reach and impact of its Young Health Programme to support non-profit organisations that are working in the area of youth health and disease prevention. Since the launch of the programme in 2018 thirteen grants have been awarded to organisations with a charitable purpose across the African Cluster. More information on the Step Up! grants programme and our Step Up! grantees and their projects can be found here.  

NCD National Screening campaign

Non-Communicable Diseases (NCD) National Screening campaign in partnership with the Department of Health

AstraZeneca is currently working in partnership with the National Department of Health to implement a national screening programme for Non-Communicable Diseases. The national screening programme will empower and equip community health outreach workers with the right knowledge and tools to complete comprehensive health screening at community household level using digital devices. The digital device automatically connects the community intervention with health systems and other government sectors ensuring the availability of real-time data. Based on data collected, it is possible to guide the individual towards either the health promotion and disease prevention activities or to enter the health system into the correct level of care for appropriate interventions, in the shortest period and most efficient manner.


Phakamisa v/t [phaga’mi:sa]: IsiZulu for elevate, lift, raise, uplift, upliftment.

Phakamisa is AstraZeneca’s access to healthcare initiative in South Africa.

Through partnerships with multiple healthcare stakeholders we aim to improve the health outcomes for patients in South Africa and reduce the burden of non-communicable diseases on South Africa’s public healthcare system. The Programme specifically addresses early detection of disease, promotion of primary prevention, and access to care.

Phakamisa, which means ‘to uplift’ in Zulu, is delivered through a three-pillared approach, with a current focus on improving breast and prostate cancer management in the public sector:

  • Training –  supporting healthcare worker capacity building across all levels of care, from Primary Care Clinics and Community Healthcare Centres to District and Tertiary Hospitals, to ensure effective diagnosis and enhanced referral systems. 
  • Awareness – raising awareness to empower patients, community healthcare workers and healthcare professionals of NCDs with a focus on self-examination, identification, improved referral timelines that result in early diagnosis and timeous intervention and care for better treatment outcomes.
  • Access – ensuring that patients are able to access clinics early with minimal pit stops within the referral pathway, providing adequate access to care before the progression of the disease.


Africa PUMUA Initiative

PUMUA is a Swahili word that means ‘Breathe’

The Africa PUMUA Initiative is AstraZeneca's innovative programme committed to Redefining Asthma Care in Africa. Through partnership with Governments, Healthcare Professionals and Societies, and AstraZeneca, the Initiative aims to improve paediatric and adult asthma management across public and private sectors with a focus on:

  • Local health system strengthening
  • Health worker capacity building
  • Awareness and education
  • Equitable access to AstraZeneca’s respiratory medicines

The Initiative forms part of AstraZeneca’s sustainability commitment to deliver improved accessibility, acceptability, affordability and availability of quality care in Africa.

Kamba ya Shanga

Kamba Ya Shanga, is a Swahili term for ‘a beautiful string of beads’. The string of beads represents the link between the patient, the pharmacist, and the doctor, transforming the ecosystem for patients.

Pharmacists play a critical role in the continuance of care for patients . Our Kamba Ya Shanga initiative, currently active in South Africa and Kenya,  is a pharmacist-led disease management and referral programme aimed at improving patient outcomes for chronic conditions, connecting all key healthcare players along the patient’s disease management journey.  Through the programme patients will be uniquely identified by the pharmacist, have their chronic disease treatment and medication monitored, receive support that ensures optimal treatment and correct use of devices; and be seamlessly referred by the Pharmacist to their General Practitioner should further consultation be required.

Patient Support Websites

Our patient support websites offer a valuable resource for people living with asthma, Cardio-Renal and Metabolic diseases (CVRM), providing tools, information, and support.

The sites are more than just accessible information, they offer an extension of care that reaches beyond the consulting room and offers practical support plans and downloadable resources.

Click the links and explore

  • Yes2Life – Understanding and treating cardiovascular, renal, and metabolic diseases as interlinked conditions
  • – Understanding Asthma
  • Yes2Nurture  – RSV support for caregivers of young patients



Clinical Research & Development

AstraZeneca Africa Cluster has proven its willingness to play a significant role in international R&D through a strong investment in clinical studies, across therapeutic areas, with added value for local doctors and patients.

We have had significant involvement in the rich pipeline of candidate drugs emerging from R&D sites. High quality work with specialists and primary care physicians in South Africa over the past years has resulted in a steady increase of trial work being awarded to the Clinical Research Department in South Africa, which attained key country status in 2000.

Our focus is on adding value, not only to our global company’s research and development programme, but also to the society within which we operate; the institutions and academic centres of medical excellence with whom we have partnered in our work; and finally to the patients whom we serve. South Africa has and continues to participate in many key AstraZeneca projects over all therapeutic areas and is experienced in conducting phase I-IV trials.

Currently, AstraZeneca South Africa is involved in 26 trials spanning different therapeutic areas and is working with 45 clinical centres (March 2022). We also conduct CRO led studies locally.

In Kenya AZ is conducting the sickle cell disease in paediatrics study, the first R&D phase III trial initiated in Kenya for sickle cell disease in paediatrics. This research commitment in a population where non-communicable diseases are exponentially increasing with minimal intervention, supports our bold ambition of improving lives

Research studies

Critically aware of the increasing health challenges in Africa and the need for quality scientific data to properly manage and treat potentially life-threatening illnesses, we participate in global research studies in our key markets strengthening Africa’s medical research capability to solve local challenges.

Global research studies in our markets:

DISCOVER REGISTRY: A global real-world evidence registry of patients with type 2 diabetes mellitus that is moving the frontiers of Medicine.

DISCOVER STUDY: A global observational study of patients with type 2 diabetes mellitus who are starting second-line glucose-lowering therapy.

COPVAR: A cross-sectional study of patients with severe COPD to assess patient perception of symptom variability in Middle East & Africa countries.

DECLARE: DECLARE (Dapagliflozin Effect on Cardiovascular Events)-TIMI 58 a  randomised, double-blinded, placebo-controlled, multi-centre trial designed to evaluate the effect of Forxiga compared with placebo on CV outcomes in adults with T2D at risk of CV events, including patients with multiple CV risk factors or established CV disease.

SABINA: A multi-centre observational study on the prescription patterns of short-acting Beta-2 agonists, SABA, and its implications on asthma control.

HESTIA STUDIES: A study to evaluate the effect of Ticagrelor in reducing the rate of Vaso-Occlusive Crises in Paediatric patients with Sickle Cell Disease.

Scientific research studies conducted in collaboration with external stakeholders:

A prospective, longitudinal, epidemiological study to categorise and electronically capture data of all respiratory patients attending the outpatients clinic at the Charlotte Maxeke Johannesburg Academic Hospital (CMJAH) in South Africa. The study will aim to electronically capture data as well as attempt to standardise the clinical assessment and therapeutic interventions on all patients attending the various pulmonology outpatient clinics at the CMJAH. The study will also introduce various tools validated for assessment of the different pulmonary disease entities and use these objective scoring systems to assess patient severity and response to therapy.

Lung function predictive equations for healthy South African children and adults: The Paediatric and Adult African Spirometry Working Group. This study will aim to determine the normal reference equations for spirometry in South African adults and children.


At AstraZeneca, we’re driven by innovation and our commitment to make a real-life difference in patients’ lives. That difference starts with you. We need people like you who share our passion for science and determination to meet patients’ needs around the world.

From medical science to sales & marketing, we’re on a mission to turn ideas into life-changing medicines. If you’re inspired by the possibilities of science to make a difference and ready to discover what you can do – join us.


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This information is used by the company to further enhance our understanding of the safety profile of our medicines and ensure we can treat patients effectively.

If you would like to report an adverse event for an AstraZeneca product, please contact AstraZeneca Safety Managers:





Phone:           +27 11 797 6193 / 6000
Fax:                +27 11 797 6019

Out of hours emergency contact details

South Africa             +27 72 758 7638



Phone:           00 225 05 76 82 17 70


Out of hours emergency contact details

Angola                                        +244 94 359 5906

Ghana                                         +233 501412918

Kenya                                         +254 721200017

Nigeria                                        +234 (0) 803 979 0404

Uganda                                       +256 75 030 8830

Sub Saharan Africa                     +225 05 7682 1770


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