For investor audiences and financial/business media only
Growth momentum continues. On track to deliver ambition of $80 billion in Total Revenue in 2030
In the first half we saw strong performance and continued pipeline delivery, including six key positive Phase III programmes and eight first approvals in major markets.
We continue to invest at pace in our transformative technologies, and in our commercial execution to bring our innovative medicines to patients around the globe and drive growth beyond 2030.
Key performance elements for H1 2026
(Growth numbers at constant exchange rates)
Total Revenue up 6%, with double-digit growth in Oncology and Rare Disease
Core Operating profit and Core EPS increased 11%
Interim dividend increased 3 cents to $1.06 per share (79.5 pence, 10.32 SEK)
30 approvals in major regions since Q4 2025 results
How did AstraZeneca perform financially?
| Revenue and EPS Summary | H1 2026 | Q2 2026 | ||||
|---|---|---|---|---|---|---|
| $m | % Change Actual | % Change CER | $m | % Change Actual | % Change CER | |
| Product Sales | 28,896 | 8 | 5 | 14,510 | 5 | 4 |
| Alliance Revenue | 1,699 | 31 | 29 | 874 | 34 | 33 |
| Product Revenue | 30,595 | 9 | 6 | 15,384 | 6 | 5 |
| Collaboration Revenue | 77 | (6) | (9) | - | n/m | n/m |
| Total Revenue | 30,672 | 9 | 6 | 15,384 | 6 | 5 |
| Reported EPS ($) | 3.60 | 4 | 3 | 1.61 | 2 | (2) |
| Core EPS ($) | 5.21 | 12 | 11 | 2.63 | 21 | 18 |
GUIDANCE3
RECONFIRMED
Which Therapy Areas drove growth?
H1 2026 Total Revenue by Therapy Area. Growth at CER.
46% of revenue and the largest Therapy Area
36% of revenue. Respiratory & Immunology grew +9%, CVRM (−12%), Infectious Disease (-26%)
16% of revenue
What were the pipeline highlights?
projects in our pipeline new molecular entities (NMEs) or major life-cycle management in Phase II or Phase III NMEs in our late-stage pipeline
NMEs under review
183
116
21
4
Matthew Bowden
Company Secretary
AstraZeneca PLC
References
1. Constant exchange rates. The differences between Actual Change and CER Change are due to foreign exchange movements between periods in 2026 vs. 2025. CER financial measures are not accounted for according to generally accepted accounting principles (GAAP) because they remove the effects of currency movements from Reported results.
2. Core financial measures are adjusted to exclude certain items. The differences between Reported and Core measures are primarily due to costs relating to the amortisation of intangibles, impairments, legal settlements and restructuring charges. A full reconciliation between Reported EPS and Core EPS is provided in Tables 10 and 11 in the Financial Performance section of this document.
3. The Company is unable to provide guidance on a Reported basis because it cannot reliably forecast material elements of the Reported results, including any fair value adjustments arising on acquisition-related liabilities, intangible asset impairment charges and legal settlement provisions. Please refer to the Cautionary statements section regarding forward-looking statements at the end of this announcement.