We are committed to innovation and constantly pushing the boundaries of science


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Publications in 2014

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Commitment to science

Our commitment to science is reflected in our track record of publications. Here are a few recent examples of high impact and high quality publications co-authored by AstraZeneca and/or MedImmune scientists.

In silico design of context-responsive mammalian promoters with user-defined functionality

Published: 30 August 2017

Area: R&D (Early Development)

AstraZeneca/MedImmune author:  Suzanne Gibson, Diane Hatton

Fractionated dosing improves preclinical therapeutic index of pyrrolobenzodiazepine-containing antibody drug conjugates

Published: 23 August 2017

Area: Oncology

AstraZeneca/MedImmune author: Mary Jane Masson Hinrichs, Pauline Ryan, Bo Zheng

Gut check on diabesity: leveraging gut mechanisms for the treatment of type 2 diabetes and obesity

Published: 10 August 2017

Area: CVMD

AstraZeneca/MedImmune author:  Sarah Will, David Hornigold, David Baker

Role of CD11c+ T-bet+ B cells in human health and disease

Published: 11 June 2017

Area: RIA

AstraZeneca/MedImmune author:  Jodi Karnell, Varsha Kumar, Jingya Wang, Shu Wang, Elisaveta Voynova, Rachel Ettinger

Expression of PD-L1 and other immunotherapeutic targets in thymic epithelial tumors

Published: 03 August 2017

Area: Oncology

AstraZeneca/MedImmune author:  Keith Steele

High-throughput quantitation of Fc-containing recombinant proteins in cell culture supernatant by fluorescence polarization spectroscopy

Published: 01 October 2017

Area: R&D (Early Development)

AstraZeneca/MedImmune author:  Mike Jenns

A phase 1 study to evaluate the safety and pharmacokinetics of MEDI8852, an anti-influenza A monoclonal antibody, in healthy adult volunteers

Published: 22 August 2017

Area: Infection

AstraZeneca/MedImmune author: Raburn Mallory

Targeting phosphatase-dependent proteoglycan switch for rheumatoid arthritis therapy

Published: 20 May 2015

Area: Inflammation and Autoimmunity 

AstraZeneca/MedImmune author: Tomas Mustelin

IL-33 drives airway hyper-responsiveness through IL-13-mediated mast cell: airway smooth muscle crosstalk

Published: 16 March 2015

Area: Respiratory

AstraZeneca/MedImmune author:  Richard May (MedImmune)  

Low-frequency coding variants at 6p22.2-6p21.31 and 20q11.21 are associated with lung cancer risk in Chinese populations

Published: 7 May 2015

Area: Oncology

AstraZeneca/MedImmune author: Brandon Higgs