Publications

Early discovery

30 June 2017 Details

Published:

Nature Biotechnology, published online ahead of print 30 June 2017, doi:10.1038/nmicrobiol.2017.104

Author(s):

Gao, Ning

Respiratory

28 June 2017 Details

Published:

The Lancet Respiratory Medicine, published online ahead of print 28 June 2017, DOI: 10.1016/S2213-2600(17)30207-2

Author(s):

Rennard, Stephen I

Early discovery

26 June 2017 Details

Published:

Nature Communications, published online 26 June 2017, doi:10.1038/ncomms15475

Author(s):

Karp, Natasha

Oncology

23 June 2017 Details

Published:

Journal of Clinical Oncology, published online ahead of print 23 June 2017, DOI: 10.1200/JCO.2017.72.2967

Author(s):

Morgan, Shethah R; Frigault, Melanie Show all authors Clark, Edwin; Handzel, Amir

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Switching the light off in the discovery of new cancer therapies against KRAS

Oncology

14 June 2017 Details

Published:

Science Translational Medicine, published 14 June 2017, DOI: 10.1126/scitranslmed.aal5253

Author(s):

Ross, Sarah; Lyne, Paul; Rooney, Claire; Hanson, Lyndsey L Show all authors Ellston, Rebecca A; Klein, Stephanie; Staniszewska, Anna D; Whalley, Nichola M

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Switching the light off in the discovery of new cancer therapies against KRAS

Respiratory

01 June 2017 Details

Published:

The Lancet Respiratory Medicine, published online ahead of print1 June 2017, DOI:http://dx.doi.org/10.1016/S2213-2600(17)30218-7

Author(s):

Da Silva, Carla; Fagerås, Malin; Johnson, Anthony Show all authors Jauhiainen, Alexandra; Sethi, Tariq

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CompEx: novel exacerbation measure may speed up asthma drug development

Early discovery

11 May 2017 Details

Published:

Clinical Microbiology Reviews, published online ahead of print 11 May 2017, DOI: 10.1128/CMR.00111

Author(s):

Sjö, Peter

Early discovery

10 May 2017 Details

Published:

Science Advances 10 May 2017: Vol. 3, no. 5, e1700933 DOI: 10.1126/sciadv.1700933

Author(s):

Phillips, Christopher Show all authors Fisher, David; Pollard, Hannah K; Truman, Caroline M

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Revealing the dynamic structure of ATM

Oncology

10 May 2017 Details

Published:

Journal of Clinical Oncology - published online ahead of print May 10, 2017 DOI: 10.1200/JCO.2017.73.0143

Author(s):

Lindemann, Justin PO; Ambrose, Helen J; Schiavon, Gaia Show all authors Barrett, Carl; Dougherty, Brian; Foxley, Andrew; McEwen, Robert; Pass, Martin

Early discovery

26 April 2017 Details

Published:

Nature, published online 26 April 2017 DOI: 10.1038/nature22309

Author(s):

Dekker, Niek; Edman, Karl; Geschwinder, Stefan Show all authors Hermansson, Nils-Olov; Johansson, Patrik; Snijder, Arjan; Sundström, Linda; Brown, Dean G; Grebner, Christoph; Thornton, Peter

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New structural insight into the highly challenging drug target PAR2 helps paves the way for future therapies in inflammatory pain

Early Clinical Development

03 April 2017 Details

Published:

The Lancet, published online 3 April 2017 DOI: http://dx.doi.org/10.1016/S0140-6736(17)30823-1

Author(s):

Webber, Lorraine

CVMD

22 February 2017 Details

Published:

The Lancet (2017) Published online 22 February 2017 doi:10.1016/S2213-8587(17)30061-X

Author(s):

Carlsson, Björn; Karlsson, Cecilia

Related Articles

Early intervention for pre-diabetes shown to prevent long-term complications

Respiratory

06 February 2017 Details

Published:

Nature Genetics (2017) Published online 06 February 2017 doi:10.1038/ng.3752

Author(s):

Rennard, Stephen I; Hardin, Megan

Early discovery

09 January 2017 Details

Published:

Nature Chemical Biology (2017) Published online 09 January 2017 DOI:10.1038/nchembio.2270

Author(s):

Johansson, Patrik Show all authors Hongming Chen, Margareta E Ek, Arjan Snijder

Oncology

16 December 2016 Details

Published:

Cancer Discovery Published 16 December 2016 DOI: 10.1158/2159-8290.CD-15-1523

Author(s):

Chris Morrow Show all authors Anne Goeppert, Aaron Smith, Mandy Lawson, Joanne Wilson

Related Articles

New directions for ER+ breast cancer treatment: do estrogen receptor gene mutations hold the key?

Oncology

12 December 2016 Details

Published:

Nature Chemistry 12 Dec 2016 DOI:10.1038/nchem.2670

Author(s):

Raubo, Piotr

Discovery Sciences

09 December 2016 Details

Published:

Nature Reviews Drug Discovery Published online: 09 December 2016 DOI:10.1038/nrd.2016.213

Author(s):

Goodnow, Robert (ex AZ)

Oncology

07 December 2016 Details

Published:

Science Translational Medicine 07 Dec 2016: Vol. 8, Issue 368, pp. 368ra172 Published online: 7 December 2016 DOI:10.1126/scitranslmed.aag0976

Author(s):

Yang, Pamela All authors Guo, Qiuli; Zhang, Xiaolin; Bai, Yu; Chen, Kan; Cheng, Zack; Cohen-Rabbie, Sarit; Wang, Yingchun; Xu, Jessie; Yin, Lucy; Zhang, David

Related Articles

Novel pre-clinical brain metastases models show good translation to clinical setting

CVMD

05 December 2016 Details

Published:

Nature Biomedical Engineering 1, Article number: 0003 (2016) Published online: 5 December 2016 DOI:10.1038/s41551-016-0003

Author(s):

Drowley, Lauren All authors Wang, Qing-Dong; Plowright, Alleyn T

Oncology

21 November 2016 Details

Published:

Nature Medicine (2016) Published online: 21 November 2016 DOI: 10.1038/nm.4239

Author(s):

Andrew Hughes

CVMD

18 November 2016 Details

Published:

Chem. Rev., Article, Published online: 18 November 2016 DOI: 10.1021/acs.chemrev.6b00466

Author(s):

Johan Johansson

CVMD

01 November 2016 Details

Published:

Circulation. 2016;CIRCULATIONAHA.116.022064 DOI: http://dx.doi.org/10.1161/CIRCULATIONAHA.116.022064

Author(s):

Wang, Qing-Dong All authors Spaeter, Daniela

Related Articles

A new role for IGF1 signalling in driving fat tissue formation in heart disease

CVMD

27 October 2016 Details

Published:

Circulation. 2016;CIRCULATIONAHA.116.024014 DOI: http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024014

Author(s):

Carlsson, Leif G

Oncology

26 October 2016 Details

Published:

Science Translational Medicine 26 Oct 2016: Vol. 8, Issue 362, pp. 362ps17 DOI: 10.1126/scitranslmed.aaf9246

Author(s):

O’Connor, Mark

Oncology

24 October 2016 Details

Published:

Nature Medicine 22, 1303–1313 (2016), published online 24 October 2016 DOI:10.1038/nm.4198

Author(s):

McEachern, Kristen (ex AZ)

Oncology

24 October 2016 Details

Published:

Nature Chemical Biology (2016) Published online 24 October 2016, doi:10.1038/nchembio.2210

Author(s):

Raymond Chen All authors Dale, Ian L; Robb, Graeme R; Bobby, Romel; Boiko, Scott; Callis, Rowena J; Clark, Edwin; Flavell, Liz; Holdgate, Geoffrey A; McAlister, Mark; Petteruti, Philip; Saif, Sakina; Stratton, Natalie; Whittaker, David T E; Wilson, David M; Yao, Yi

CVMD

17 October 2016 Details

Published:

Nature Chemical Biology (2016), published online 17 October 2016 doi:10.1038/nchembio.2203

Author(s):

Bjorn Over All authors Hilgendorf, Constanze; Lewis, Richard; Perry, Matthew, Tyrchan, Christian

Oncology

11 October 2016 Details

Published:

Nature Reviews Clinical Oncology DOI:10.1038/nrclinonc.2016.162 Published online 11 Oct 2016

Author(s):

Waterton, John (ex AZ)

CVMD

06 October 2016 Details

Published:

Nature Communications 7, Article number: 12962 (2016) doi:10.1038/ncomms12962

Author(s):

Bergman, Joakim

Respiratory

01 October 2016 Details

Published:

The Lancet, Volume 4, No. 10, p797–806, October 2016 DOI: http://dx.doi.org/10.1016/S2213-2600(16)30227-2

Author(s):

Marie Cullberg, Mohib K Uddin, Kai Richter, et al.

Early Clinical Development

28 September 2016 Details

Published:

Nature 538, 248–252 (13 October 2016) doi:10.1038/nature19806

Author(s):

Vaag, Allan

Oncology

27 September 2016 Details

Published:

Cell Discovery 2, Article number: 16031 (2016) doi:10.1038/celldisc.2016.31

Author(s):

De Bruin, Elizabeth C

CVMD

22 September 2016 Details

Published:

Cell Metabolism (2016) http://dx.doi.org/10.1016/j.cmet.2016.08.020

Author(s):

Ämmälä, Carina All authors Eliasson, Pernilla; Andersson, Eva-Marie; Smith, David M; Andréasson, Anne-Christine; Bjursell, Magnus; Clausen, Maryam; Sabirsh, Alan

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Innovative pancreatic research expands treatment horizons for people with type 2 diabetes

Oncology

15 September 2016 Details

Published:

Cell, Volume 167, Issue 1, p260–274.e22, 22 September 2016 DOI: http://dx.doi.org/10.1016/j.cell.2016.08.041

Author(s):

O'Connor, Mark J

Oncology

09 September 2016 Details

Published:

The Lancet Oncology

Author(s):

Hodgson, Darren Show all authors Fielding, Anitra; Spencer, Stuart; Lowe, Elizabeth; Sovak, Mika (all GMD)

Oncology

07 September 2016 Details

Published:

Nature Reviews Materials 1, Article number: 16069 (2016) doi:10.1038/natrevmats.2016.69

Author(s):

Ashford, Marianne B

Oncology

05 September 2016 Details

Published:

Nature Chemical Biology (2016) Published online 05 September 2016 doi:10.1038/nchembio.2174

Author(s):

Su, Qibin All authors Belmonte, Matthew; Aquila, Brian; Hird, Alex; Lamb, Michelle; Rawlins, Philip B; Su, Nancy; Tentarelli, Sharon; Grimster, Neil

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Opening up a treasure trove of new drug target opportunities

Respiratory

26 August 2016 Details

Published:

The Lancet Respiratory Medicine DOI: 10.1016/S2213-2600(16)30227-2

Author(s):

Cullberg, Marie Show all authors Puu, Margareta; Richter, Kai; Keen, Christina; Uddin, Mohib K; Larsson, Bengt; Anna Malmgren

Related Articles

Breakthrough research revealing novel drivers of cardiometabolic diseases published in Science

Cardiovascular and Metabolic diseases

19 August 2016 Details

Published:

Science 19 Aug 2016: Vol. 353, Issue 6301, pp. 827-830 DOI: 10.1126/science.aad6970

Author(s):

Gan, Li-Ming

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Breakthrough research revealing novel drivers of cardiometabolic diseases published in Science

Oncology

15 August 2016 Details

Published:

Nature Chemical Biology; 15 August 2016, doi: 10.1038/nchembio.2148

Author(s):

Durant, Stephen All authors McWhirter, Claire; Nissink, Willem; Debreczeni, Judit

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Uncovering world’s first structural clues to inhibiting an emerging DNA Damage Response target area for future anti-cancer therapy

Oncology

27 June 2016 Details

Published:

Journal of Clinical Oncology DOI: 10.1200/JCO.2016.66.7162 Journal of Clinical Oncology 34, no. 28 (October 2016) 3375-3382.

Author(s):

Thress, Kenneth All authors Barrett, Carl; Cantarini, Mireille V

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Uncovering world’s first structural clues to inhibiting an emerging DNA Damage Response target area for future anti-cancer therapy

Oncology

18 June 2016 Details

Published:

The New England Journal of Medicine DOI: 10.1056/NEJMoa1505971

Author(s):

Rennard, Stephen I

Related Articles

Uncovering world’s first structural clues to inhibiting an emerging DNA Damage Response target area for future anti-cancer therapy

Oncology

13 June 2016 Details

Published:

Cancer Cell, Volume 29, Issue 6, p832–845, 13 June 2016

Author(s):

Barry, Simon T All authors Wilson, Zena

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New study published in ‘Cancer Cell’ furthers understanding role of CXCR2 in pancreatic cancer

Oncology

09 June 2016 Details

Published:

Nature 534, 272–276 (09 June 2016) doi:10.1038/nature17963

Author(s):

Cosulich, Sabina C All authors McWhirter, Claire; Barratt, Derek G; Klinowska, Teresa

Oncology

01 June 2016 Details

Published:

Published online 01 June 2016; Nature Reviews Clinical Oncology (2016) doi:10.1038/nrclinonc.2016.79

Author(s):

Clack, Glen (ex AZ)

Medicinal chemistry

01 June 2016 Details

Published:

Advanced Drug Delivery Reviews; Volume 101, 1 June 2016, Pages 42–61. http://dx.doi.org/10.1016/j.addr.2016.03.013

Author(s):

Bjorn Over

Oncology

18 May 2016 Details

Published:

Nature 534, 272–276 (09 June 2016) Published online 18 May 2016 DOI:10.1038/nature17963

Author(s):

Cosulich, Sabina C All authors McWhirter, Claire; Barratt, Derek G; Klinowska, Teresa

Oncology

16 May 2016 Details

Published:

Advanced Drug Delivery Reviews DOI:10.1016/j.addr.2016.04.025

Author(s):

Hare, Jennifer I Show all authors Ashford, Marianne B; Barry, Simon T; Puri, Sanyogitta

Oncology

15 May 2016 Details

Published:

Nature Medicine DOI: 10.1158/2159-8290.CD-15-1246 Published 13 May 2016

Author(s):

Kilgour, Elaine Show all authors Smith, Neil R; Rooney, Claire

Personalised healthcare

13 May 2016 Details

Published:

Nature Reviews Drug Discovery 15, 369–370 (2016); Published Online May 13, 2016; DOI:10.1038/nrd.2016.74

Author(s):

Reischl, Joachim

Oncology

13 May 2016 Details

Published:

Published Online May 13, 2016; doi: 10.1158/2159-8290.CD-15-1246

Author(s):

Kilgour, Elaine All authors Smith, Neil R; Rooney, Claire

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Clinical trial data unveil a driver of FGFR inhibitor response in gastric cancer

Respiratory

12 May 2016 Details

Published:

12 May 2016 N Engl J Med 2016; 374:1811-1821DOI: 10.1056/NEJMoa1505971

Author(s):

Stephen I Rennard

Neuroscience

09 May 2016 Details

Published:

Published online 9 May 2016; Nature Medicine 22, 649–656 (2016) doi:10.1038/nm.4096

Author(s):

Brandon, Nick All authors Cross, Alan J

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AstraZeneca and Lieber Institute for Brain Development publish discovery of novel protein associated with schizophrenia

Oncology

05 May 2016 Details

Published:

Published online 5 May 2016; Nature Medicine 22, 464–471 (2016) doi:10.1038/nm.4089

Author(s):

Barrett, Carl

Oncology

29 April 2016 Details

Published:

Published Online April, 2016; Advanced Drug Delivery Reviews http://dx.doi.org/10.1016/j.addr.2016.04.025

Author(s):

Jennifer I Hare, Marianne B Ashford, Simon T Barry, et al.

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Defining a new approach to developing nanomedicines for cancer therapies

Oncology

26 April 2016 Details

Published:

Published online 26 April 2016; Nature Reviews Cancer 16, 319–329 (2016) doi:10.1038/nrc.2016.35

Author(s):

Carr, Hedley All authors McEwen, Robert

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New genomic classification approach strengthens early cancer trial design

CVMD

11 April 2016 Details

Published:

Advanced Drug Delivery Reviews DOI: 10.1016/j.addr.2016.03.013

Author(s):

Bjorn Over

Oncology

15 March 2016 Details

Published:

Immunity: Volume 44, Issue 3, 15 March 2016, Pages 698–711 DOI: http://dx.doi.org/10.1016/j.immuni.2016.02.025

Author(s):

Angell, Helen K All others Valge-Archer, Viia

Oncology

24 February 2016 Details

Published:

Science Translational Medicine 24 Feb 2016: Vol. 8, Issue 327, pp. 327ra26 DOI: 10.1126/scitranslmed.aad6352

Author(s):

Angell, Helen K All authors Valge-Archer, Viia

Oncology

10 February 2016 Details

Published:

Science Translational Medicine 10 Feb 2016: Vol. 8, Issue 325, pp. 325ra17 DOI: 10.1126/scitranslmed.aad2355

Author(s):

Barry, Simon T All authors Ashton, Susan; Jewsbury, Philip J; Ashford, Marianne B; Cadogan, Elaine; Howes, Colin; Murray, Jim; Goodwin, Richard; Polanska, Urszula M; Reimer, Corinne; Smith, Aaron; Swales, John G; Taylor, Paula J; Wilson, Joanne

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AstraZeneca and BIND Therapeutics publish AZD2811 ACCURINS® data in Science Translational Medicine

Publications

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