Publications

R&D /Discovery

14 April 2020 Details

Published:

Nature Communications

Author(s):

David Lowe Show all authors Janet Saunders, Paul Devine, Stacey Chin, Elizabeth England, James Button, Christopher Lloyd, Nicholas Bond

R&D /Discovery

11 March 2020 Details

Published:

Science Advances

Author(s):

Richard Goodwin Show all authors John Swales, Nicole Strittmatter, Ryan Bragg, Jasper Komen

R&D /Discovery

11 February 2020 Details

Published:

Cell Death Discovery

Author(s):

Dave Smith Show all authors Ulf Borjesson, Martina Fitzek, Ieuan Roberts, Nidhal Selmi

R&D /Discovery

27 January 2020 Details

Published:

Nature

Author(s):

Rhiannon David Show all authors Douglas Ferguson, Alexander MacDonald, Peter Pop-Damkov

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Cryo-electron microscopy

R&D/Oncology

29 July 2019 Details

Published:

Nature Immunology

Author(s):

R&D/Oncology

17 July 2019 Details

Published:

Cancer Discovery

Author(s):

Iwanka Kozarewa

R&D/Oncology

10 July 2019 Details

Published:

Cancer Cell

Author(s):

Mark O’Connor

R&D/Oncology

10 July 2019 Details

Published:

Nature Reviews Drug Discovery

Author(s):

Dan Freeman

R&D/Respiratory

01 July 2019 Details

Published:

Nature Immunology

Author(s):

Yoichiro Ohne Show all authors Alison Humbles, Jingya Wang, Jinchneg Wu

R&D/Oncology

17 June 2019 Details

Published:

Nature Communications

Author(s):

Jonathan Dry

R&D/Discovery

13 June 2019 Details

Published:

Nature Communications

Author(s):

Ralph Minter Show all authors Jason Breed, Judit Debreczeni, Christopher Stubbs, Jonathan Tart

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Using novel tools to inhibit challenging targets

R&D/CVRM

10 June 2019 Details

Published:

Journal of the American College of Cardiology

Author(s):

Li-Ming Gan

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Video – The heritability of coronary artery disease

R&D/Oncology

02 June 2019 Details

Published:

New England Journal of Medicine

Author(s):

Dan Stetson

R&D/Oncology

02 May 2019 Details

Published:

Nature Communications

Author(s):

Paul Smith

R&D/Oncology

25 April 2019 Details

Published:

Nature Medicine

Author(s):

Emma Dean Show all authors Donal Landers

R&D/Discovery

22 April 2019 Details

Published:

Nature Chemistry

Author(s):

James Douglas

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Lighting the path to simplified chemical reactions

R&D/Discovery

19 April 2019 Details

Published:

Science

Author(s):

Pinar Akcakaya Show all authors Marcello Maresca, Michelle Porritt, Michaela Morlock

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Video – Monitoring CRISPR gene editing in vivo

R&D/CVRM

28 March 2019 Details

Published:

Cell Stem Cell

Author(s):

Qing-Dong Wang Show all authors Aurelie Bornot, Mei Ding, Henrik Andersson, Magnus Polla, Lauren Drowley, Maryam Clausen, Alleyn T Plowright, Ian Barrett

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Video – Stimulating cardiac cell growth

R&D/Oncology

14 March 2019 Details

Published:

JCO Precision Oncology

Author(s):

Dan Stetson

R&D/Respiratory

07 March 2019 Details

Published:

Communications Biology

Author(s):

Gabriela Marchetti, Timothy Burwell, Norman Peterson, Jennifer Cann, Richard Hanna, Qing Li, Emily Ongstad, Jonathan Boyd, Maureen Kennedy, Weiguang Zhao, Keith Rickert, Joseph Grimsby, William Dall’Acqua, Herren Wu, Ping Tsui, Jack Borrok, Ruchi Gupta

R&D/Oncology

28 February 2019 Details

Published:

Nature Reviews Clinical Oncology

Author(s):

Andrew Reynolds, Elizabeth Kuczynski

R&D/Discovery

25 February 2019 Details

Published:

Nature Structural & Molecular Biology

Author(s):

Emanuela Cuomo Show all authors Ben Taylor

R&D/Discovery

20 February 2019 Details

Published:

Nature Communications

Author(s):

Li-Ming Gan, Lagerström-Fermér M, Carlsson L, Arfvidsson C, Egnell A-C, Rudvik A, Kjaer M, Fritsche-Danielson R

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Designing the first-ever trial for an mRNA-based therapeutic

R&D/Oncology

18 February 2019 Details

Published:

Nature Immunology

Author(s):

Philip Brohawn, Brandon Higgs

R&D/Discovery

04 February 2019 Details

Published:

Nature Chemical Biology

Author(s):

Jens Petersen, Gangadhara Gangadhara, Göran Dahl, Jens Petersen, Rebecca Rae, Jenny Gunnarsson, Stefan Blaho, Linda Öster, Helena Lindmark, Kostas Karabelas, Nils Pemberton, Christian Tyrchan, Matthew Perry, Tineke Papavoine, Michael Mogemark

R&D/CVRM

30 January 2019 Details

Published:

Nature

Author(s):

Stefano Bartesaghi, Henrik Palmgrem, Xioa-Rong Peng

R&D/Respiratory

29 January 2019 Details

Published:

Immunity

Author(s):

Benjamin Kemp, Matthew Robinson

R&D/Oncology

08 January 2019 Details

Published:

Nature Communications

Author(s):

Josep Forment, Stephen Durant

R&D/Discovery

02 January 2019 Details

Published:

Nature Communications

Author(s):

Catherine Bardelle, Ulf Borjesson, Matther Collier, Paul Harper, Darren Plant, Helen Plant, Mark Wigglesworth, Roger Clark, Kirsty Rich

R&D/CVRM

26 December 2018 Details

Published:

The New England Journal of Medicine

Author(s):

Adam Platt, Sophia Cameron-Christie, Jan Fleckner, Slavé Petrovski, Carolina Haefliger, Ruth March

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The dawn of a new era in chronic kidney disease

R&D/CVRM

18 December 2018 Details

Published:

Circulation

Author(s):

Qing-Dong Wang

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Uncovering the right targets: Refining cardiovascular regenerative medicine

R&D/Oncology

17 December 2018 Details

Published:

Nature Communications

Author(s):

Adriana Tron, Ammar Adam, Brian Aquila, Mathew Belmonte, Elisabetta Chiarparin, Justin Cidado, Kevin Embrey, Eric Gangl, Frank Giboons, David Hargreaves, Adam Hendricks, Alex Hird, Jeffrey Johannes, Jason Kettle, Michelle Lamb, Martin Packer, Bo Peng, Phillip Rawlins, Alwin Schuller, Paul Secrist, Nancy Su, David Wilson, Wenzhen Yang, Ye Qing, XiaoLan Zheng, Steven Kazmirski, Daniel Robbins, Ed Clarke, Stephen Fawell

R&D/Discovery

10 December 2018 Details

Published:

Nature Catalysis

Author(s):

Per-Ola Norrby, Elaine Limé

R&D/CVRM

03 December 2018 Details

Published:

Nature Metabolism

Author(s):

Stefan Hallén, Matthew Harms

R&D/CVRM

22 October 2018 Details

Published:

Nature Catalysis

Author(s):

Ulrik Jurva, Justyna Kulig, Shalini Andersson, Emre Isin

R&D/Oncology

18 October 2018 Details

Published:

Cancer Discovery

Author(s):

Jon Travers, Simon Barry, Kim Maratea, Paula Taylor, Elizabeth Pease

R&D/CVRM

17 October 2018 Details

Published:

Science Advances

Author(s):

Carina Ämmälä, William J Drury III, Laurent Knerr, Ingela Ahlstedt, Pia Stillemark-Billton, Charlotte Wennberg-Huldt, Eva-Marie Andersson, Eric Valeur, Rasmus Jansson-Löfmark, David Janzén, Linda Sundström, Johan Meuller, Josefine Claesson, Patrik Andersson, Camilla Johansson, Shalini Andersson

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AstraZeneca shows potential of gene silencing in pancreatic cells

R&D/Discovery

12 October 2018 Details

Published:

Nature Reviews Drug Discovery

Author(s):

Jane Escott

R&D/Respiratory

04 October 2018 Details

Published:

European Heart Journal, ehy531,https://doi.org/10.1093/eurheartj/ehy531

Author(s):

Lynne Murray

R&D/CVRM

12 September 2018 Details

Published:

Nature Catalysis

Author(s):

Joakim Bergman, Andrei Iosub

R&D/Discovery

12 September 2018 Details

Published:

Nature

Author(s):

Pinar Akcakaya, Mick Fellows, Michelle Porritt, Mike Firth, Alba Carreras, Frank Seeliger, Mikael Bjursell, Roberto Nitsch, Mohammad Bohlooly, Marcello Maresca, Tania Baccega, Lorenz May

R&D/CVRM

27 August 2018 Details

Published:

European Heart Journal, ehy531,https://doi.org/10.1093/eurheartj/ehy531

Author(s):

Li-Ming Gan Show all authors Malin Broberg, Maria Lagerstrom-Fermer.

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A PROMISing future: New insights to disease drivers and potential new diagnostic markers in heart disease

R&D/CVRM

24 August 2018 Details

Published:

Nature Reviews Drug Discovery

Author(s):

Jonas Boström Show all authors Dean Brown

R&D/CVRM

09 August 2018 Details

Published:

European Heart Journal, ehy419,https://doi.org/10.1093/eurheartj/ehy419

Author(s):

Erik Michaëlsson Show all authors Eva-Lotte Lindstedt

Related content

A PROMISing future: New insights to disease drivers and potential new diagnostic markers in heart disease

R&D/Discovery

03 August 2018 Details

Published:

2018. American Journal of Respiratory and Critical Care Medicine. 1 Oct 2018; 198(7):928-940. doi: 10.1164/rccm.201706-1110OC.

Author(s):

Han Si, Rebecca Halpin, Todd Creasy, Claudie Bantsimba-Malanda, Ron Herbst

R&D/CVRM

02 August 2018 Details

Published:

EBioMedicine

Author(s):

Wiseman, John W

R&D/CVRM

23 June 2018 Details

Published:

Published online 22 Jun 2018: Lancet. doi:10.1016/S0140-6736(18)30726-8.

Author(s):

Philip Ambery, Victoria Parker, Lan-Feng Tsai, Darren Robertson, Meena Jain, Marcella Petrone, Cristina Rondinone, Boaz Hirshberg, Lutz Jermutus

R&D/Oncology

20 June 2018 Details

Published:

Science Advances 20 Jun 2018: Vol. 4, no. 6, eaat1719 DOI: 10.1126/sciadv.aat1719

Author(s):

Durant, Stephen Show all authors Pass, Martin Riches, Lucy Garcia-Trinidad, Antonio Fok, Jacqueline Hunt, Thomas Pike, Kurt G Wilson, Joanne Smith, Aaron Colclough, Nicola Pilla Reddy, Venkatesh Sykes, Andy Janefeldt, Annika Johnström, Peter Ling, Stephanie Orme, Jonathon Barrett, Ian Jones, Gemma Roudier, Martine Pierce, Andrew Cronin, Anna Chapman, Melissa Illingworth, Ruth

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Preclinical data of the ATM inhibitor, AZD1390 show promising results in brain tumour models

Publications

Commitment to science

Our commitment to science is reflected in our track record of publications. Here are a few recent examples of high impact publications co-authored by AstraZeneca scientists.