Publications

Oncology

25 August 2017 Details

Published:

Journal of Clinical Oncology, published online ahead of print 25 August 2017, DOI: 10.1200/JCO.2017.74.7576.

Author(s):

Thress, Kenneth; Mann, Helen; Ghiorghiu, Serban

CVMD

15 August 2017 Details

Published:

Cell Research. 2017; 27: 1157-1177. doi:10.1038/cr.2017.103

Author(s):

Wang, Qing-Dong

CVMD

15 August 2017 Details

Published:

JAMA. 2017;318(7):637-646. doi:10.1001/jama.2017.10169

Author(s):

Vaag, Allan

CVMD

20 July 2017 Details

Published:

Nature Communications, published online ahead of print 20 July 2017, doi:10.1038/s41467-017-00118-1

Author(s):

Wang, Qing-Dong

Oncology

14 July 2017 Details

Published:

Nature Communications, published online ahead of print 14 July 2017, DOI: 10.1038/ncomms16111

Author(s):

Guillard, Sandrine; Minter, Ralph; Phillips, Christopher Show all authors Breed, Jason; Debreczeni, Judit; Overman, Ross; Tart, Jonathan; Kolasinska-Zwierz, Paulina; Marwood, Rose

Related Articles

Finding a cancer ‘off switch’ for mutant Ras

Early discovery

30 June 2017 Details

Published:

Nature Biotechnology, published online ahead of print 30 June 2017, doi:10.1038/nmicrobiol.2017.104

Author(s):

Gao, Ning

Respiratory

28 June 2017 Details

Published:

The Lancet Respiratory Medicine, published online ahead of print 28 June 2017, DOI: 10.1016/S2213-2600(17)30207-2

Author(s):

Rennard, Stephen I

Early discovery

26 June 2017 Details

Published:

Nature Communications, published online 26 June 2017, doi:10.1038/ncomms15475

Author(s):

Karp, Natasha

Oncology

23 June 2017 Details

Published:

Journal of Clinical Oncology, published online ahead of print 23 June 2017, DOI: 10.1200/JCO.2017.72.2967

Author(s):

Morgan, Shethah R; Frigault, Melanie Show all authors Clark, Edwin; Handzel, Amir

Oncology

14 June 2017 Details

Published:

Science Translational Medicine, published 14 June 2017, DOI: 10.1126/scitranslmed.aal5253

Author(s):

Ross, Sarah; Lyne, Paul; Rooney, Claire; Hanson, Lyndsey L Show all authors Ellston, Rebecca A; Klein, Stephanie; Staniszewska, Anna D; Whalley, Nichola M

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Switching the light off in the discovery of new cancer therapies against KRAS

Respiratory

01 June 2017 Details

Published:

The Lancet Respiratory Medicine, published online ahead of print1 June 2017, DOI:http://dx.doi.org/10.1016/S2213-2600(17)30218-7

Author(s):

Da Silva, Carla; Fagerås, Malin; Johnson, Anthony Show all authors Jauhiainen, Alexandra; Sethi, Tariq

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CompEx: novel exacerbation measure may speed up asthma drug development

Early discovery

11 May 2017 Details

Published:

Clinical Microbiology Reviews, published online ahead of print 11 May 2017, DOI: 10.1128/CMR.00111

Author(s):

Sjö, Peter

Early discovery

10 May 2017 Details

Published:

Science Advances 10 May 2017: Vol. 3, no. 5, e1700933 DOI: 10.1126/sciadv.1700933

Author(s):

Phillips, Christopher Show all authors Fisher, David; Pollard, Hannah K; Truman, Caroline M

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Revealing the dynamic structure of ATM

Oncology

10 May 2017 Details

Published:

Journal of Clinical Oncology - published online ahead of print May 10, 2017 DOI: 10.1200/JCO.2017.73.0143

Author(s):

Lindemann, Justin PO; Ambrose, Helen J; Schiavon, Gaia Show all authors Barrett, Carl; Dougherty, Brian; Foxley, Andrew; McEwen, Robert; Pass, Martin

Early discovery

26 April 2017 Details

Published:

Nature, published online 26 April 2017 DOI: 10.1038/nature22309

Author(s):

Dekker, Niek; Edman, Karl; Geschwinder, Stefan Show all authors Hermansson, Nils-Olov; Johansson, Patrik; Snijder, Arjan; Sundström, Linda; Brown, Dean G; Grebner, Christoph; Thornton, Peter

Related Articles

New structural insight into the highly challenging drug target PAR2 helps paves the way for future therapies in inflammatory pain

Early Clinical Development

03 April 2017 Details

Published:

The Lancet, published online 3 April 2017 DOI: http://dx.doi.org/10.1016/S0140-6736(17)30823-1

Author(s):

Webber, Lorraine

CVMD

22 February 2017 Details

Published:

The Lancet (2017) Published online 22 February 2017 doi:10.1016/S2213-8587(17)30061-X

Author(s):

Carlsson, Björn; Karlsson, Cecilia

Related Articles

Early intervention for pre-diabetes shown to prevent long-term complications

Respiratory

06 February 2017 Details

Published:

Nature Genetics (2017) Published online 06 February 2017 doi:10.1038/ng.3752

Author(s):

Rennard, Stephen I; Hardin, Megan

Early discovery

09 January 2017 Details

Published:

Nature Chemical Biology (2017) Published online 09 January 2017 DOI:10.1038/nchembio.2270

Author(s):

Johansson, Patrik Show all authors Hongming Chen, Margareta E Ek, Arjan Snijder

Oncology

16 December 2016 Details

Published:

Cancer Discovery Published 16 December 2016 DOI: 10.1158/2159-8290.CD-15-1523

Author(s):

Chris Morrow Show all authors Anne Goeppert, Aaron Smith, Mandy Lawson, Joanne Wilson

Related Articles

New directions for ER+ breast cancer treatment: do estrogen receptor gene mutations hold the key?

Oncology

12 December 2016 Details

Published:

Nature Chemistry 12 Dec 2016 DOI:10.1038/nchem.2670

Author(s):

Raubo, Piotr

Discovery Sciences

09 December 2016 Details

Published:

Nature Reviews Drug Discovery Published online: 09 December 2016 DOI:10.1038/nrd.2016.213

Author(s):

Goodnow, Robert (ex AZ)

Oncology

07 December 2016 Details

Published:

Science Translational Medicine 07 Dec 2016: Vol. 8, Issue 368, pp. 368ra172 Published online: 7 December 2016 DOI:10.1126/scitranslmed.aag0976

Author(s):

Yang, Pamela All authors Guo, Qiuli; Zhang, Xiaolin; Bai, Yu; Chen, Kan; Cheng, Zack; Cohen-Rabbie, Sarit; Wang, Yingchun; Xu, Jessie; Yin, Lucy; Zhang, David

Related Articles

Novel pre-clinical brain metastases models show good translation to clinical setting

CVMD

05 December 2016 Details

Published:

Nature Biomedical Engineering 1, Article number: 0003 (2016) Published online: 5 December 2016 DOI:10.1038/s41551-016-0003

Author(s):

Drowley, Lauren All authors Wang, Qing-Dong; Plowright, Alleyn T

Oncology

21 November 2016 Details

Published:

Nature Medicine (2016) Published online: 21 November 2016 DOI: 10.1038/nm.4239

Author(s):

Andrew Hughes

CVMD

18 November 2016 Details

Published:

Chem. Rev., Article, Published online: 18 November 2016 DOI: 10.1021/acs.chemrev.6b00466

Author(s):

Johan Johansson

CVMD

01 November 2016 Details

Published:

Circulation. 2016;CIRCULATIONAHA.116.022064 DOI: http://dx.doi.org/10.1161/CIRCULATIONAHA.116.022064

Author(s):

Wang, Qing-Dong All authors Spaeter, Daniela

Related Articles

A new role for IGF1 signalling in driving fat tissue formation in heart disease

CVMD

27 October 2016 Details

Published:

Circulation. 2016;CIRCULATIONAHA.116.024014 DOI: http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024014

Author(s):

Carlsson, Leif G

Oncology

26 October 2016 Details

Published:

Science Translational Medicine 26 Oct 2016: Vol. 8, Issue 362, pp. 362ps17 DOI: 10.1126/scitranslmed.aaf9246

Author(s):

O’Connor, Mark

Oncology

24 October 2016 Details

Published:

Nature Medicine 22, 1303–1313 (2016), published online 24 October 2016 DOI:10.1038/nm.4198

Author(s):

McEachern, Kristen (ex AZ)

Oncology

24 October 2016 Details

Published:

Nature Chemical Biology (2016) Published online 24 October 2016, doi:10.1038/nchembio.2210

Author(s):

Raymond Chen All authors Dale, Ian L; Robb, Graeme R; Bobby, Romel; Boiko, Scott; Callis, Rowena J; Clark, Edwin; Flavell, Liz; Holdgate, Geoffrey A; McAlister, Mark; Petteruti, Philip; Saif, Sakina; Stratton, Natalie; Whittaker, David T E; Wilson, David M; Yao, Yi

CVMD

17 October 2016 Details

Published:

Nature Chemical Biology (2016), published online 17 October 2016 doi:10.1038/nchembio.2203

Author(s):

Bjorn Over All authors Hilgendorf, Constanze; Lewis, Richard; Perry, Matthew, Tyrchan, Christian

Oncology

11 October 2016 Details

Published:

Nature Reviews Clinical Oncology DOI:10.1038/nrclinonc.2016.162 Published online 11 Oct 2016

Author(s):

Waterton, John (ex AZ)

CVMD

06 October 2016 Details

Published:

Nature Communications 7, Article number: 12962 (2016) doi:10.1038/ncomms12962

Author(s):

Bergman, Joakim

Respiratory

01 October 2016 Details

Published:

The Lancet, Volume 4, No. 10, p797–806, October 2016 DOI: http://dx.doi.org/10.1016/S2213-2600(16)30227-2

Author(s):

Marie Cullberg, Mohib K Uddin, Kai Richter, et al.

Early Clinical Development

28 September 2016 Details

Published:

Nature 538, 248–252 (13 October 2016) doi:10.1038/nature19806

Author(s):

Vaag, Allan

Oncology

27 September 2016 Details

Published:

Cell Discovery 2, Article number: 16031 (2016) doi:10.1038/celldisc.2016.31

Author(s):

De Bruin, Elizabeth C

CVMD

22 September 2016 Details

Published:

Cell Metabolism (2016) http://dx.doi.org/10.1016/j.cmet.2016.08.020

Author(s):

Ämmälä, Carina All authors Eliasson, Pernilla; Andersson, Eva-Marie; Smith, David M; Andréasson, Anne-Christine; Bjursell, Magnus; Clausen, Maryam; Sabirsh, Alan

Related Articles

Innovative pancreatic research expands treatment horizons for people with type 2 diabetes

Oncology

15 September 2016 Details

Published:

Cell, Volume 167, Issue 1, p260–274.e22, 22 September 2016 DOI: http://dx.doi.org/10.1016/j.cell.2016.08.041

Author(s):

O'Connor, Mark J

Oncology

09 September 2016 Details

Published:

The Lancet Oncology

Author(s):

Hodgson, Darren Show all authors Fielding, Anitra; Spencer, Stuart; Lowe, Elizabeth; Sovak, Mika (all GMD)

Oncology

07 September 2016 Details

Published:

Nature Reviews Materials 1, Article number: 16069 (2016) doi:10.1038/natrevmats.2016.69

Author(s):

Ashford, Marianne B

Oncology

05 September 2016 Details

Published:

Nature Chemical Biology (2016) Published online 05 September 2016 doi:10.1038/nchembio.2174

Author(s):

Su, Qibin All authors Belmonte, Matthew; Aquila, Brian; Hird, Alex; Lamb, Michelle; Rawlins, Philip B; Su, Nancy; Tentarelli, Sharon; Grimster, Neil

Related Articles

Opening up a treasure trove of new drug target opportunities

Respiratory

26 August 2016 Details

Published:

The Lancet Respiratory Medicine DOI: 10.1016/S2213-2600(16)30227-2

Author(s):

Cullberg, Marie Show all authors Puu, Margareta; Richter, Kai; Keen, Christina; Uddin, Mohib K; Larsson, Bengt; Anna Malmgren

Related Articles

Breakthrough research revealing novel drivers of cardiometabolic diseases published in Science

Cardiovascular and Metabolic diseases

19 August 2016 Details

Published:

Science 19 Aug 2016: Vol. 353, Issue 6301, pp. 827-830 DOI: 10.1126/science.aad6970

Author(s):

Gan, Li-Ming

Related Articles

Breakthrough research revealing novel drivers of cardiometabolic diseases published in Science

Oncology

15 August 2016 Details

Published:

Nature Chemical Biology; 15 August 2016, doi: 10.1038/nchembio.2148

Author(s):

Durant, Stephen All authors McWhirter, Claire; Nissink, Willem; Debreczeni, Judit

Related Articles

Uncovering world’s first structural clues to inhibiting an emerging DNA Damage Response target area for future anti-cancer therapy

Oncology

27 June 2016 Details

Published:

Journal of Clinical Oncology DOI: 10.1200/JCO.2016.66.7162 Journal of Clinical Oncology 34, no. 28 (October 2016) 3375-3382.

Author(s):

Thress, Kenneth All authors Barrett, Carl; Cantarini, Mireille V

Related Articles

Uncovering world’s first structural clues to inhibiting an emerging DNA Damage Response target area for future anti-cancer therapy

Oncology

18 June 2016 Details

Published:

The New England Journal of Medicine DOI: 10.1056/NEJMoa1505971

Author(s):

Rennard, Stephen I

Related Articles

Uncovering world’s first structural clues to inhibiting an emerging DNA Damage Response target area for future anti-cancer therapy

Oncology

13 June 2016 Details

Published:

Cancer Cell, Volume 29, Issue 6, p832–845, 13 June 2016

Author(s):

Barry, Simon T All authors Wilson, Zena

Related Articles

New study published in ‘Cancer Cell’ furthers understanding role of CXCR2 in pancreatic cancer

Oncology

09 June 2016 Details

Published:

Nature 534, 272–276 (09 June 2016) doi:10.1038/nature17963

Author(s):

Cosulich, Sabina C All authors McWhirter, Claire; Barratt, Derek G; Klinowska, Teresa

Oncology

01 June 2016 Details

Published:

Published online 01 June 2016; Nature Reviews Clinical Oncology (2016) doi:10.1038/nrclinonc.2016.79

Author(s):

Clack, Glen (ex AZ)

Medicinal chemistry

01 June 2016 Details

Published:

Advanced Drug Delivery Reviews; Volume 101, 1 June 2016, Pages 42–61. http://dx.doi.org/10.1016/j.addr.2016.03.013

Author(s):

Bjorn Over

Oncology

18 May 2016 Details

Published:

Nature 534, 272–276 (09 June 2016) Published online 18 May 2016 DOI:10.1038/nature17963

Author(s):

Cosulich, Sabina C All authors McWhirter, Claire; Barratt, Derek G; Klinowska, Teresa

Oncology

16 May 2016 Details

Published:

Advanced Drug Delivery Reviews DOI:10.1016/j.addr.2016.04.025

Author(s):

Hare, Jennifer I Show all authors Ashford, Marianne B; Barry, Simon T; Puri, Sanyogitta

Oncology

15 May 2016 Details

Published:

Nature Medicine DOI: 10.1158/2159-8290.CD-15-1246 Published 13 May 2016

Author(s):

Kilgour, Elaine Show all authors Smith, Neil R; Rooney, Claire

Personalised healthcare

13 May 2016 Details

Published:

Nature Reviews Drug Discovery 15, 369–370 (2016); Published Online May 13, 2016; DOI:10.1038/nrd.2016.74

Author(s):

Reischl, Joachim

Oncology

13 May 2016 Details

Published:

Published Online May 13, 2016; doi: 10.1158/2159-8290.CD-15-1246

Author(s):

Kilgour, Elaine All authors Smith, Neil R; Rooney, Claire

Related Articles

Clinical trial data unveil a driver of FGFR inhibitor response in gastric cancer

Respiratory

12 May 2016 Details

Published:

12 May 2016 N Engl J Med 2016; 374:1811-1821DOI: 10.1056/NEJMoa1505971

Author(s):

Stephen I Rennard

Neuroscience

09 May 2016 Details

Published:

Published online 9 May 2016; Nature Medicine 22, 649–656 (2016) doi:10.1038/nm.4096

Author(s):

Brandon, Nick All authors Cross, Alan J

Related Articles

AstraZeneca and Lieber Institute for Brain Development publish discovery of novel protein associated with schizophrenia

Oncology

05 May 2016 Details

Published:

Published online 5 May 2016; Nature Medicine 22, 464–471 (2016) doi:10.1038/nm.4089

Author(s):

Barrett, Carl

Oncology

29 April 2016 Details

Published:

Published Online April, 2016; Advanced Drug Delivery Reviews http://dx.doi.org/10.1016/j.addr.2016.04.025

Author(s):

Jennifer I Hare, Marianne B Ashford, Simon T Barry, et al.

Related Articles

Defining a new approach to developing nanomedicines for cancer therapies

Oncology

26 April 2016 Details

Published:

Published online 26 April 2016; Nature Reviews Cancer 16, 319–329 (2016) doi:10.1038/nrc.2016.35

Author(s):

Carr, Hedley All authors McEwen, Robert

Related Articles

New genomic classification approach strengthens early cancer trial design

CVMD

11 April 2016 Details

Published:

Advanced Drug Delivery Reviews DOI: 10.1016/j.addr.2016.03.013

Author(s):

Bjorn Over

Oncology

15 March 2016 Details

Published:

Immunity: Volume 44, Issue 3, 15 March 2016, Pages 698–711 DOI: http://dx.doi.org/10.1016/j.immuni.2016.02.025

Author(s):

Angell, Helen K All others Valge-Archer, Viia

Oncology

24 February 2016 Details

Published:

Science Translational Medicine 24 Feb 2016: Vol. 8, Issue 327, pp. 327ra26 DOI: 10.1126/scitranslmed.aad6352

Author(s):

Angell, Helen K All authors Valge-Archer, Viia

Oncology

10 February 2016 Details

Published:

Science Translational Medicine 10 Feb 2016: Vol. 8, Issue 325, pp. 325ra17 DOI: 10.1126/scitranslmed.aad2355

Author(s):

Barry, Simon T All authors Ashton, Susan; Jewsbury, Philip J; Ashford, Marianne B; Cadogan, Elaine; Howes, Colin; Murray, Jim; Goodwin, Richard; Polanska, Urszula M; Reimer, Corinne; Smith, Aaron; Swales, John G; Taylor, Paula J; Wilson, Joanne

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AstraZeneca and BIND Therapeutics publish AZD2811 ACCURINS® data in Science Translational Medicine

Publications

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