EcoPharmacoVigilance Dashboard

EcoPharmacoVigilance Dashboard

As a result of patient use and manufacture, pharmaceuticals are found in the aquatic environment, typically in nanograms per litre concentrations.  AstraZeneca conducts a robust environmental risk assessment for its products and reports a programme of safe discharge from manufacturing facilities.

As part of its ongoing EcoPharmacoVigilance AstraZeneca also undertakes a quarterly search of the published, peer-reviewed scientific literature for reports of detection of environmental residues of our active pharmaceutical ingredients (APIs) in order to understand real world environmental risks. Of 40 APIs included in the search, reports of measured data have been found for 32 of those APIs to date. These measured environmental concentrations (MECs) have been extracted and formatted for transparent visualization. The EcoPharmacoVigilance Dashboard presents these MECs in a risk relationship relative to the Predicted No Effect Concentrations (PNECs) used for environmental assessment. Calculated RQs that are displayed as 0.0 denote risk quotients that are lower than 1x10-9.

This dashboard reflects data collected in literature searches performed between Q4 2020 and Q4 2024. Data capacity limitations of the dashboard prevent the entirety of all collected MECs to be displayed as one.

An archived version of this dashboard is available here containing historic data up to and including Q3 2023.   

The EcoPharmacoVigilance Dashboard was developed in association with Simomics Ltd. To get the best experience, we recommend using the latest version of Chrome, Edge, Safari or Firefox.