Messenger RNA (mRNA) is a single stranded RNA that conveys genetic information from DNA to the ribosome, where it is translated into protein products.
mRNA genetic information is in the sequence of nucleotides. Each consists of a base (adenine, guanine, cytosine, uracil), a five-carbon sugar (ribose in the case of RNA), and a phosphate group. Since mRNA can be used as a blue-print for producing proteins in cells, it can be chemically synthesised as a therapeutic to produce intracellular proteins needed to correct disease. Modifications are made to the mRNA structure to make it more stable and less immunogenic.
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